Stem cells and motor recovery after stroke
نویسندگان
چکیده
منابع مشابه
Stem cells for enhancing recovery after stroke: a review.
The potential application for stem cell therapy is vast, and development for use in ischaemic stroke is still in its infancy. Access to stem cells for research is contentious; however, stem cells are obtainable from both animal and human. Despite a limited understanding of their mechanisms of action, clinical trials assessing stem cells in human stroke have been performed. Trials are also under...
متن کاملHuman umbilical mesenchymal stem cells promote recovery after ischemic stroke.
BACKGROUND AND PURPOSE Stroke is a cerebrovascular defect that leads to many adverse neurological complications. Current pharmacological treatments for stroke remain unclear in their effectiveness, whereas stem cell transplantation shows considerable promise. Previously, we have shown that human umbilical mesenchymal stem cells (HUMSCs) can differentiate into neurons in neuronal-conditioned med...
متن کاملDrugs to Enhance Motor Recovery After Stroke.
Abstract—Among the therapeutic strategies under study to improve long-term outcome after stroke are drugs targeting events that underlie recovery. Drugs that enhance recovery are separate from those that promote neuroprotection or reperfusion in patients with stroke. Recovery-based drugs have distinct therapeutic targets that are related to plasticity and growth after stroke, and in general, im...
متن کاملRecovery of motor function after stroke.
The human brain possesses a remarkable ability to adapt in response to changing anatomical (e.g., aging) or environmental modifications. This form of neuroplasticity is important at all stages of life but is critical in neurological disorders such as amblyopia and stroke. This review focuses upon our new understanding of possible mechanisms underlying functional deficits evidenced after adult-o...
متن کاملRecovery and rehabilitation in stroke: stem cells.
The recent demonstration that neurons for transplantation can be generated from stem cells and that the adult brain produces new neurons in response to stroke has raised hope for the development of a stem cell therapy for patients affected with this disorder. In this review we propose a road map to the clinic and describe the different scientific tasks that need to be accomplished to move stem ...
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ژورنال
عنوان ژورنال: Annals of Physical and Rehabilitation Medicine
سال: 2014
ISSN: 1877-0657
DOI: 10.1016/j.rehab.2014.08.008